September 24, 2020

Human Echinococcosis Mortality in the United States, 1990–2007

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We identified 41 echinococcosis-related deaths among US residents during the period 1990–2007 (Table 1). Age-adjusted mortality rates were higher in males (0.012 per 106) than in females (0.005 per 106), with males more than 2 times as likely to die from echinococcosis than were females (adjusted rate ratio = 2.2, 95% CI 1.3–3.9).

Although these data are population based and contain large numbers of observations, death certificates likely underreport causes of death and may contain errors, which have been attributed to a variety of factors.

Fatal echinococcosis may be more common in the United States than currently appreciated. Echinococcosis causes a mortality burden in the United States that may be modified by increased prevention and control efforts, including vaccine development for adult cestode carriers and livestock [13]. Given the presence of echinococcosis mortality in US-born persons, and the risk of travel-related exposure, hygiene precautions should be advised for individuals traveling to Echinococcus species endemic areas. Clinicians should be aware of the diagnosis, particularly in foreign-born patients from Echinococcus endemic areas, and should consider tropical infectious disease consultation early.<<<Read More>>>